Kaposi’s varicelliform eruption is a rare and potentially fatal viral infection caused mainly by reactivation of herpes simplex virus. It concomitantly occurs with. Disseminated herpes or vaccinia in the setting of underlying skin diseases is known as Kaposi’s varicelliform eruption (KVE). Patients typically present with. It is autosomal dominant in transmission. Patients with DWD are prone to frequent superinfection including the rare complication of Kaposi varicelliform eruption.

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The distribution of affected skin reflects the crucial role of skin barrier impairment since Kaposi varicelliform eruption begins in areas of underlying dermatosis.

From Wikipedia, the free encyclopedia. PubMed Links to PubMed. The first ended fatally, and specialized animal laboratory studies or autopsy findings were nonobtainable.

Kaposi’s varicelliform eruption eczema herpeticum is the name given to a distinct cutaneous eruption caused by herpes simplex and certain other viruses that infect persons with preexisting dermatosis. Junctional adhesion molecule overexpression in Kaposi varicelliform eruption skin lesions – as a possible herpes virus entry site. Although the pathogenesis of KVE is not completely elucidated, it is well recognized that the patients with diseases with underlying skin barrier damage and those with immune deficiencies are the most susceptible.

A Kaposi’s varicelliform eruption in erythrodermic psoriasis. Clear Turn Off Turn On. Prognosis Kaposi varicelliform eruption is a serious condition that may have fatal outcomes.

Financial support and sponsorship Nil. The most common complications are both bacterial infection that varicelliforn lead to sepsis and viremia, with involvement of other organs.

How to cite this URL: The diagnosis is clinical[ 1 ].

Sign in to download free article PDFs Sign in to access your varicelliflrm Sign in to your personal account. There has been a significant increase in the communications of KVE cases since due to the drastic increase in HSV infection in the world. We also highlight clinical features, associations and therapeutic options.


KVE was first described by Moritz Kaposi in the 19 th century, who assumed it was a fungal infection, whereas Juliysber argued that it was caused by bacterias. The mechanisms underlying the pathogenesis of viral reactivation in Kaposi varicelliform eruption remain incompletely understood. It concomitantly occurs with pre-existing skin conditions, mostly atopic dermatitis, so it is predominately found in faricelliform. Epub Jun Both cell-mediated and humoral immunity dysfunction are implicated.

Support Center Support Center. You can help by adding to it. Viral culture and direct fluorescence antibody staining on Tzanck smear are the most reliable techniques for herpes simplex virus detection.

Kaposi’s Varicelliform Eruption

This inaugural topographic distribution may lead to a delayed diagnosis because the eruption is often confused with the pre-existing condition. It is held that defective skin barrier acting in conjunction with immune deficiencies seems to lead to the development of the disease.

Create a personal account to register for email alerts with links to free full-text articles. Kaposi’s varicelliform eruption associated with the use of tacrolimus ointment in two neonates. Differential Diagnosis Kaposi varicelliform eruption may be confused with various conditions: Privacy Policy Terms of Use. None, Conflict of Interest: Declaration of patient consent The authors certify that they have obtained all appropriate patient consent forms.

In five patients a skin biopsy was taken, showing intraepidermal vesicle and peripheral ballooning degeneration further confirming the diagnosis. Introduction Kaposi varicelliform eruption, also called eczema herpeticum, refers to a disseminated skin infection due to a virus that usually leads to localized vesicular eruptions, occurring in a patient with an underlying cutaneous disease.


Kaposi’s varicelliform eruption: A case series

Sign in to customize your interests Sign in to your personal account. Virus-related cutaneous conditions Herpes simplex virus-associated diseases. Online since 15 th March ‘ This infection affects multiple organsincluding the eyesbrainlungand liverand can be fatal.

Kaposi’s varicelliform eruption affecting conjunctival mucosa and periocular area. Shenoy MM, Suchitra U. However, adult cases have been reported. The most serious ophthalmological sequela is herpetic keratitis which may lead to vision loss resulting from corneal scarring. Sign in to save your search Sign in to your personal account.

Kaposi’s Varicelliform Eruption | JAMA Dermatology | JAMA Network

Widespread clusters of vesicles and erosions covered by hemorrhagic crusts. StatPearls Publishing; Jan. We report a case of a three-year-old atopic child who presented with extensive vesicular eruption suggestive of Kaposi’s varicelliform eruptlon. Kaposi’s varicelliform eruption is a rare and potentially fatal viral infection caused mainly by reactivation of herpes simplex virus.

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Eczema herpeticum – Wikipedia

Purchase access Subscribe to the journal. It has also been suggested by some workers that other viruses may be responsible for a clinically similar condition, but proof of this is still lacking. History and Physical Patients with Kaposi varicelliform eruption present with a sudden skin eruption of painful clusters of umbilicated vesicles and pustules.

European Journal of Pediatric Dermatology. Kaposi Varicelliform Eruption – StatPearls. Five patients required acyclovir suppressive therapy due to relapses acyclovir mg per day for 6—12 months.